LOW LEVELS OF MICRORNA-10A IN CARDIOVASCULAR ENDOTHELIUM AND BLOOD SERUM ARE RELATED TO HUMAN ATHEROSCLEROTIC DISEASE

Low Levels of MicroRNA-10a in Cardiovascular Endothelium and Blood Serum Are Related to Human Atherosclerotic Disease

Background.MicroRNA-10a (miR-10a) inhibits transcriptional factor GATA6 to repress inflammatory GATA6/VCAM-1 Équipement signaling, which is regulated by blood flow to affect endothelial function/dysfunction.This study aimed to identify the expression patterns of miR-10a/GATA6/VCAM-1 in vivo and study their implications in the pathophysiology of hu

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Attenuating effect of Indian mustard (Brassica juncea) seed and its nano formulation on arsenic induced-oxidative stress and associated genotoxicity in rat

Objective: Arsenic (As) has been in the forefront of toxicological research due to its continual worldwide human exposure and its adverse effects including genotoxicity.The study assessed the potential ameliorative effect of Indian mustard seeds (Brassica juncea) and their nanoparticles against arsenic toxicity.Methods: Male Wistar rats were used f

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